1. Take backup of site-packages.
cp -r /usr/local/lib/python2.7/site-packages/ /tmp/site-packages
2. Truncate that directory
rm -rf /usr/local/lib/python2.7/site-packages/
3. Now try the same
virtualenv --no-site-packages --distribute -p /usr/bin/python3.3 ~/.virtualenvs/pywork3
4. To install without pip
virtualenv --no-site-packages --distribute -p /usr/bin/python3.3 ~/.virtualenvs/pywork3 --no-pip