LeetCode 题解(133): Repeated DNA Sequences

题目:

All DNA is composed of a series of nucleotides abbreviated as A, C, G, and T, for example: "ACGAATTCCG". When studying DNA, it is sometimes useful to identify repeated sequences within the DNA.

Write a function to find all the 10-letter-long sequences (substrings) that occur more than once in a DNA molecule.

For example,

Given s = "AAAAACCCCCAAAAACCCCCCAAAAAGGGTTT",

Return:
["AAAAACCCCC", "CCCCCAAAAA"].

题解:

用Python Dict直接将每一个长度为10的子串作为key保存出现次数。但Java无法通过memory limit。需要将"A", "C", "G", "T"映射为"0x0", "0x1", "0x2", "0x3",再用int的低20 bit作为key。

C++版:

class Solution {
public:
    vector<string> findRepeatedDnaSequences(string s) {
        vector<string> result;
        if(s.length() <= 10)
            return result;
            
        unordered_map<int, int> count;
        int key = 0;
        for(int i = 0; i < s.length(); i++) {
            int current = 0;
            switch(s[i]) {
                case 'A': current = 0x0;
                          break;
                case 'C': current = 0x1;
                          break;
                case 'G': current = 0x2;
                          break;
                case 'T': current = 0x3;
                          break;
            }
            key = ((key << 2) | current) & 0xFFFFF;
            if(i < 9)
                continue;
            if(count.find(key) == count.end()) {
                count.insert(pair<int, int>(key, 1));
            } else if(count[key] == 1) {
                result.push_back(s.substr(i-9, 10));
                count[key]++;
            }
        }
        return result;
    }
};

Java版:

public class Solution {
    public List<String> findRepeatedDnaSequences(String s) {
        List<String> result = new ArrayList<>();
        if(s.length() <= 10)
            return result;
        Map<String, Integer> count = new HashMap<>();
        for(int i = 0; i <= s.length() - 10; i++) {
            String current = s.substring(i, i+9);
            if(!count.containsKey(current)) {
                count.put(current, 1);
            } else if(count.get(current) == 1) {
                result.add(current);
                count.put(current, 2);
            }
        }
        return result;
    }
}

Python版:

class Solution:
    # @param {string} s
    # @return {string[]}
    def findRepeatedDnaSequences(self, s):
        d = {}
        result = []
        if len(s) <= 10:
            return []
        for i in range(len(s)-10+1):
            sub = s[i:i+10]
            if sub in d:
                d[sub] += 1
            else:
                d[sub] = 1
                
        for i in d:
            if d[i] > 1:
                result.append(i)
                
        return result


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