新加坡国立大学癌症研究所，陈蕾蕾课题组招收生物信息学博士后-CSDN博客

陈蕾蕾博士在新加坡国立大学癌症研究所担任首席研究员，其研究团队专注于癌症转录组的RNA变化研究，包括RNA编辑、可变剪接等。现招聘有生物信息学背景的博士后，要求熟悉NGS数据分析、单细胞转录组学，并具备编程技能和英文论文写作能力。成功候选人将有机会处理多种NGS数据，寻找癌症生物标记物和调控机制。

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导师简介及研究方向

陈蕾蕾博士于2012年加入新加坡国立大学癌症研究所(CSI)担任高级研究科学家，并于 2014年6月成为一名独立首席研究员。陈蕾蕾博士同时担任新加坡国立大学Yong Loo Lin医学院解剖学系的副教授的职位。课题组研究主要围绕癌症转录组的RNA changes，包括RNA编辑，可变剪接，蛋白-RNA相互作用等，及其在癌症发展中的功能作用。课题组目前有多项具有重要应用价值的课题正在推进，与多组学、临床医学、生物信息学实验室有密切合作关系。详细介绍请参考网站：

https://www.csi.nus.edu.sg/web/chen-leilei-polly/

https://careers.nus.edu.sg/NUS/job/Kent-Ridge-Research-Fellow%28Bioinformatician-Cancer-Science-Institute%29-Kent/7713744/

A postdoctoral position is available immediately in Associate Professor Polly Chen’s group for a highly motivated Ph.D. graduate with experience in Bioinformatics (computational genomics). The focus of A/P Polly Chen’s lab is on the transcriptome-wide identification of RNA changes (e.g., RNA editing, alternative splicing, altered protein-RNA interactions, etc) in tumors and the functional investigation of these changes in cancer.

招生要求

• 具有生物信息学或计算生物学博士；

• 具有NGS datasets, 单细胞转录组学分析经验者优先；

• 具有SCI论文发表经验者优先；

• 具备基本的英文文献阅读及论文写作能力，踏实肯干，具有独立工作的能力和团队协作的精神。

Candidates should have a strong background in bioinformatics, genomics/transcriptomics, computer science, statistics, or other related fields. Those who are interested in computational genomics and transcriptomics, particularly in the analysis and integration of various genomics/transcriptomics data, are encouraged to apply.

The successful candidate will analyze and integrate in-house NGS datasets (bulk and single-cell RNA-seq, spatial transcriptomics, DNA-seq, eCLIP-seq, MeDIP-seq, etc) and also utilize publicly available genomic/transcriptomic/clinical data sets to identify novel biological biomarkers/patterns and regulatory mechanisms. Candidates are required to have a strong quantitative and statistics background, as well as strong programming skills (e.g. Python, Perl, C, C++, Java, R, or other related programming knowledge), and excellent skills in handling genomic, transcriptomic, and proteomic databases.

Experience in analyzing RNA editing, alternative splicing, and RNA binding sites using the bulk and single-cell RNA-seq, eCLIP-seq, and spatial transcriptomic data is a plus. 

A Ph.D. graduate with relevant experience in areas of computational biology/bioinformatics.

Extensive knowledge and experience in working with a variety of NGS datasets, pipeline development, and algorithm development.

Strong publication track record, indicated by first-author publications in high-quality journals.

Strong analytical skills and programming skills  Ability to write/contribute to research articles, and grants and keep meticulous notes/proper scientific documentation.

Strong interpersonal, written, and oral communication skills.

A strong team focus and ability to work independently