费舍尔精确检验matlab,Fisher精确检验

本文介绍了一种高效的Fisher精确检验实现方法,该方法特别适用于基因组范围内的关联研究等大规模问题,能够以每秒250万次的速度进行单侧或双侧检验,并已验证其在样本数量达到100时的准确性。

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Fisher’s Exact Test

Matlab's implementation of Fisher's exact test only supports one-tailed tests. Other implementations on the file exchange are reportedly buggy and are far too slow for problems I'm working on. This implementation does 2.5e6 one or two-tailed tests per second and is ideally suited for genome-wide association studies or other large problems where 100s of samples and 10s to 100s of 1000s of tests are being performed.

It has been verified correct for samples sizes up to 100 and spot checked beyond that up to 1000s of samples.

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