vbm 分析_核磁共振分析软件SPM_VBM(灰质计算)_使用手册

VBM Tutorial

John Ashburner

March15,2010

1Getting Started

The data provided are a selection of T1-weighted scans from the freely available IXI dataset1. Note that the scans were acquired in the saggital orientation,but a matrix in the NIfTI headers encodes this information so SPM can treat them as axial.

The overall plan will be to

?Start up SPM.

?Check that the images are in a suitable format(Check Reg and Display buttons).

?Segment the images,to identify grey and white matter(using the SPM→Tools→New Seg-ment option).Grey matter will eventually be warped to MNI space.This step also generates “imported”images,which will be used in the next step.

?Estimate the deformations that best align the images together by iteratively registering the imported images with their average(SPM→Tools→DARTEL Tools→Run DARTEL(create Templates)).

?Generate spatially normalised and smo