MOVICS系列教程(二) COMP Module

前言

今天我们来演示MOVICS包的第二个模块，在上一篇推文中：MOVICS系列教程(一) GET Module分析后，我们得到了乳腺癌的5个亚型，那么此模块就是为了对这5种亚型间的分子特征进行展示。

因为需要上一部分的输出结果，大家必须跑完上一篇推文的代码才可以进行本篇推文的演示代码。

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主要函数

同样的，我们先来看一下这个模块用到的函数：

compSurv(): compare survival outcome and generate a Kalan-Meier curve with pairwise comparison if possible

compClinvar(): compare and summarize clinical features among different identified subtypes

compMut(): compare mutational frequency and generate an OncoPrint with significant mutations

compTMB(): compare total mutation burden among subtypes and generate distribution of Transitions and Transversions

compFGA(): compare fraction genome altered among subtypes and generate a barplot for distribution comparison

compDrugsen(): compare estimated half maximal inhibitory concentration (IC50) for drug sensitivity and generate a boxviolin for distribution comparison

compAgree(): compare agreement of current subtypes with other pre-existed classifications and generate an alluvial diagram and an agreement barplot

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