Phthalic acid mono-2-ethylhexyl ester _ MedChemExpress (MCE)

MCE 国际站：Phthalic acid mono-2-ethylhexyl ester

参考详情：Mono-(2-ethylhexyl) phthalate (MEHP) | 内源性代谢物 | MCE

CAS：4376-20-9

品牌：MedChemExpress (MCE)

存储条件：Pure form: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.

生物活性：Phthalic acid mono-2-ethylhexyl ester (MEHP) 是邻苯二甲酸二乙基己酯 (DEHP) 的主要生物活性代谢物，可抑制 CYP17[1] 的 17、20 裂解酶活性。

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研究领域：Metabolic Enzyme/Protease

作用靶点：Endogenous Metabolite

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参考文献：

[1]. Bai J, et al. Mono-2-ethylhexyl phthalate induces the expression of genes involved in fatty acid synthesis in HepG2 cells. Environ Toxicol Pharmacol. 2019 Jul;69:104-111.[2]. Chauvigné F, et al. Mono-(2-ethylhexyl) phthalate directly alters the expression of Leydig cell genes and CYP17 lyase activity in cultured rat fetal testis. PLoS One. 2011;6(11):e27172.