Tempo 是一种经典的氮氧自由基，是一种选择性的 ROS 清除剂，可在催化循环中歧化超氧化物 |MedChemExpress (MCE)

CAS：2564-83-2

品牌：MedChemExpress (MCE)

存储条件：Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.

生物活性：Tempo 是一种经典的氮氧自由基，是一种选择性的 ROS 清除剂，可在催化循环中歧化超氧化物。 Tempo 诱导 DNA 链 断裂。 Tempo 可用作伯醇氧化成醛的有机催化剂。 Tempo 具有致突变和抗氧化作用[1][2][3][4]。

参考详情：Tempo | 氮氧自由基 | MCE

  

 

参考文献：

[1]. Chen X, et al. Isocitrate dehydrogenase 2 contributes to radiation resistance of oesophageal squamous cell carcinoma via regulating mitochondrial function and ROS/pAKT signalling. Br J Cancer. 2020 May 5.

[2]. Du K, et al. Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity. Arch Toxicol. 2017 Feb;91(2):761-773.

[3]. Guo X, et al. Comparative Genotoxicity of TEMPO and 3 of Its Derivatives in Mouse Lymphoma Cells. Toxicol Sci. 2018 May 1;163(1):214-225.

[4]. Lv H, et al. TEMPO catalyzed oxidative dehydrogenation of hydrazobenzenes to azobenzenes. Org Biomol Chem. 2020 Apr 22.