Alpha-Naphthoflavone 是一种类黄酮，是一种有效的竞争性 aromatase 抑制剂 |MedChemExpress (MCE)

中文名：α-萘黄酮

CAS：604-59-1

品牌：MedChemExpress (MCE)

存储条件：4°C, protect from light

生物活性： Alpha-Naphthoflavone 是一种类黄酮，是一种有效的竞争性 aromatase 抑制剂，具有 IC50 和 Ki 分别为 0.5 和 0.2 μM[1]。 IC50 和目标：IC50：0.5 μM（芳香化酶）[1]
Ki：0.2 μM（芳香化酶）[1]

 参考详情：Alpha-Naphthoflavone (α-萘黄酮) - 仅供科研 | Aromatase抑制剂 | MCE

参考文献：

[1]. Campbell DR, et al. Flavonoid inhibition of aromatase enzyme activity in human preadipocytes. J Steroid Biochem Mol Biol. 1993 Sep;46(3):381-8.

[2]. Cheng YW, et al. Alpha-naphthoflavone induces vasorelaxation through the induction of extracellular calcium influx and NO formation in endothelium. Naunyn Schmiedebergs Arch Pharmacol. 2003 Nov;368(5):377-85.

[3]. Flores-Pérez A, et al. Apoptosis induction and inhibition of HeLa cell proliferation by alpha-naphthoflavone and resveratrol are aryl hydrocarbon receptor-independent. Chem Biol Interact. 2018 Feb 1;281:98-105.

[4]. Hao J, et al. Resveratrol supports and alpha-naphthoflavone disrupts growth of human ovarian follicles in an in vitro tissue culture model. Toxicol Appl Pharmacol. 2018 Jan 1;338:73-82.