二苯并环辛炔-PEG2K-活性酯，DBCO-PEG2K-NHS，在缓冲液中能够展现出的快速动力学特性

PEG的工厂

于 2024-05-15 17:04:21 发布

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文章标签：化学试剂

本文链接：https://blog.csdn.net/Qq__qqqqqq/article/details/138915282

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文章关键词：DBCO PEG2K NHS，二苯并环辛炔-PEG2K-活性酯，DBCO-PEG2K-NHS

一、基本信息

【性质简介】：DBCO PEG2K NHS, as an important biological coupling reagent, exhibits rapid kinetics and stability in water buffer, providing strong technical support for biomedical research and drug development. The excellent performance of this reagent is attributed to its unique molecular structure and chemical properties. In the molecular structure of DBCO PEG2K NHS, DBCO (dibenzocyclooctene) serves as an efficient click chemical reaction group that can quickly react with biomolecules containing specific functional groups, forming stable covalent bonds. This efficient reaction kinetics enables DBCO PEG2K NHS to exhibit excellent reaction rate and efficiency in the biological coupling process. Meanwhile, the introduction of PEG2K (polyethylene glycol, molecular weight 2000) not only increases the water solubility of the molecule, but also endows DBCO PEG2K NHS with good biocompatibility and stability. PEG, as a commonly used biomaterial, has good biological inertness and anti immunogenicity, which can effectively reduce the immunogenicity reaction of biological coupling products in organisms. In addition, the long chain structure of PEG can increase the flexibility of molecules, reduce steric hindrance, and further improve the coupling efficiency between DBCO PEG2K NHS and biomolecules.

【中文名】：二苯并环辛炔-PEG2K-活性酯

【英文名】：DBCO PEG2K NHS

【分子量】：2K

【结构式】：