cut from other papers

1.  Positive selection for increased dosage has been suggested to explain large tandem arrays of rRNA and histone genes (Hurles 2004 ) and is observed experimentally

in bacteria to cope with nutrient availability (Horiuchi et al. 1962 ). 

2. 2007: 

(1. Recent research including laboratory studies on synthetic polyploids indicates that genome content and gene expression can change quickly after whole genome

duplication and that cross-genome regulatory interactions are important. 

Further, recent studies are providing insights into why some gene pairs survive in duplicate, whereas others do not.

(2.  It was shown that in Arabidopsis thaliana , one paralogon (duplicated genomic region) tends to contain significantly more genes than the other [22 ].

(3,  WGD has been proposed to be a lineagesplitting force because of the subsequent occurrence of gene losses independently in different populations [23,25,26 ].

(4.  In plants, it is possible to quantify the immediate impact of WGD by studying gene expression changes in recent natural or artificial polyploids.

(5. FRI and FLC are two of the genes responsible for the flowering time in Arabidopsis.