这是基因组比对工具Mauve,一种系统高效地构建多重基因组比对在大型的进化事件,如重排和反演。多个基因组对齐方式提供新的比额表进化动力学研究和比较基因组学的研究基础。调整整个基因组是一个从根本上不同的问题,比短序列。
软件介绍
开放源码软件根据 GNU GPL 许可
淡紫色的当前版本是 2.3.1,于 11 月 11 日公布。
2.x 版本系列包含准确的新对准算法,称为渐进的淡紫色。为更全面的变化和新的功能列表。
软件优点
Mauve is a system for efficiently constructing multiple genome alignments in the presence of large-scale evolutionary events such as rearrangement and inversion. Multiple genome alignment provides a basis for research into comparative genomics and the study of evolutionary dynamics on a new scale. Aligning whole genomes is a fundamentally different problem than aligning short sequences.
相关介绍
Mauve has been developed with the idea that a multiple genome aligner should require only modest computational resources. It employs algorithmic techniques that scale well in the amount of sequence being aligned. For example, a pair of Y. pestis genomes can be aligned in under a minute, while a group of 9 divergent Enterobacterial genomes can be aligned in a few hours.
软件截图