PCR array在全球的生物学科研实验室被广泛应用,其中包括:辉瑞,罗氏, 礼来,诺华,拜耳,Harvard,Yale,Stanford 等;研究人员已发表上万篇参考文献,包括Nature、Science、PNAS 等高水平杂志,列举如下六篇供大家参考。
研究案例1:细胞凋亡通路中基因表达变化研究案例2:缺氧通路和造血干细胞的基因表达研究
Stroma-dependent apoptosis in clonal hematopoietic precursors The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their
correlates with expression of PYCARD. Location in a Hypoxic Niche.
Blood. 2009 Jan 15;113(3):649-58. Cell Stem Cell. 2010 Sep 3;7(3):380-90.
研究案例3:干扰素相关基因表达研究 研究案例4:中风与Toll样受体信号通路基因表达研究
STAT2 Mediates Innate Immunity to Dengue Virus in the Absence Identification of TLR downstream pathways in stroke patients.
of STAT1 via the Type I Interferon Receptor. Clin Biochem. 2013 Aug;46(12):1058-64.
PLoS Pathog. 2011 Feb;7(2):e1001297.
研究案例5: 乳腺癌细胞中miRNA的表达研究 研究案例6:miRNA PCR array在黑素瘤biomarker研究中的应用
An induction of microRNA, miR-7 through estrogen treatment in Signatures of microRNAs and selected microRNA target genes in human
breast carcinoma. melanoma. Cancer Res. May 2010; 70: 4163 - 4173.
Journal of Translational Medicine 2012, 10(Suppl 1):S2.