Beta-Amyloid (12-28) | Aβ12-28 | 107015-83-8 | VHHQKLVFFAEDVGSNK | GenicBio

Alzheimer's disease (AD) is a degenerative central nervous system disorder. The histopathologic features include senile plaques, which are composed primarily of insoluble aggregates of amyloid beta-protein (A beta).β-Amyloid (12-28) (Amyloid β-Protein (12-28)) is a peptide fragment of β-amyloid protein (β1-42). β-Amyloid (12-28) shows aggregation properties. β-Amyloid (12-28) has the potential for Alzheimer’s disease research.

阿尔茨海默病是一种退行性中枢神经系统疾病。组织病理学特征包括老年斑块，主要由淀粉样β蛋白（Aβ）的不溶性聚集体组成。Beta-Amyloid (12-28) 是 β-淀粉样蛋白 (1-42) 的肽片段。 β-Amyloid (12-28) 具有聚集特性。β-Amyloid (12-28) 有潜力用于阿尔茨海默氏病的研究。

序列(单字母)：VHHQKLVFFAEDVGSNK
序列(三字母):    H-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH
CAS: 107015-83-8
分子式：C89H135N25O25
分子量：1955.30

序列分析：

引用文献：

1, Structural, kinetic and cytotoxicity aspects of 12-28 beta-amyloid protein fragment: a reappraisal
Francesc Rabanal 1,  Josep M Tusell,  Lluis Sastre,  M Rosa Quintero,  Montse Cruz,  Dolors Grillo,  Miquel Pons,  Fernando Albericio,  Joan Serratosa,  Ernest Giralt
J Pept Sci. 2002 Oct;8(10):578-88. doi: 10.1002/psc.418.

2, [Changes in neurotransmission systems after the injection of beta-amyloid protein beta (12-28) in the hypothalamus and anterior thalamus of the rat].
Gonzalo-Ruiz A
Revista de Neurologia, 01 May 1999, 28(10):931-941

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