3-硝基丙酸 (β-Nitropropionic acid) 是 succinate dehydrogenase 的不可逆抑制剂 |MedChemExpress (MCE)

中文名：3-硝基丙酸

CAS：504-88-1

品牌：MedChemExpress (MCE)

存储条件：4°C, sealed storage, away from moisture and light

生物活性： 3-硝基丙酸 (β-Nitropropionic acid) 是 succinate dehydrogenase 的不可逆抑制剂。 3-Nitropropanoic acid 具有强大的抗分枝杆菌活性，MIC 值为 3.3 μM[1][2]。 IC50 和目标：琥珀酸脱氢酶[1]

 参考详情： 3-Nitropropanoic acid (β-Nitropropionic acid，3-硝基丙酸) - 仅供科研 | 琥珀酸脱氢酶抑制剂 | MCE

参考文献：

[1]. Chomcheon P, et al. 3-Nitropropionic acid (3-NPA), a potent antimycobacterial agent from endophytic fungi: is 3-NPA in some plants produced by endophytes? J Nat Prod. 2005 Jul;68(7):1103-5.

[2]. Huang LS, et al. 3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme. J Biol Chem. 2006 Mar 3;281(9):5965-72.