MCE 国际站:MDTF
品牌:MedChemExpress (MCE)
存储条件:Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
生物活性: MDTF 是一种不可切割的 ADC 接头,用于合成抗体药物偶联物 (ADC)[1]。
体外:MDTF (50 μM) 通过取代环己基环增加亲水特性,与基于 MCC 的探针相比,基于 MD 的 FRET 探针在人血浆中孵育具有相当高的自稳定率[1] .
热销产品:LAS17 | NB-598 | Corynoxine B | Ganoderol A | Mulberrin | Sobetirome | Goserelin (acetate) | DG-041 | Quercetin 3-O-(6''-O-malonyl)-β-D-glucoside | ZIP
研究领域:Antibody-drug Conjugate/ADC Related
作用靶点:ADC Linker
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
参考文献:
[1]. Dovgan I, et, al. 2-(Maleimidomethyl)-1,3-Dioxanes (MD): a Serum-Stable Self-hydrolysable Hydrophilic Alternative to Classical Maleimide Conjugation. Sci Rep. 2016 Aug 9;6:30835.