蛋白质结构模型和功能预测：I-TASSER工具的使用

I-TASSER是一款用于预测蛋白质结构和功能的工具，网站链接：https://zhanglab.ccmb.med.umich.edu/I-TASSER/

具体描述如下：

I-TASSER (Iterative Threading ASSEmbly Refinement) is a hierarchical approach to protein structure and function prediction. It first identifies structural templates from the PDB by multiple threading approach LOMETS, with full-length atomic models constructed by iterative template fragment assembly simulations. Function insights of the target are then derived by threading the 3D models through protein function database BioLiP. I-TASSER (as 'Zhang-Server') was ranked as the No 1 server for protein structure prediction in recent community-wide CASP7,