1.
Anyukhovsky EP, Sosunov EA, Plotnikov A, Gainullin RZ, Jhang JS, Marboe CC, Rosen MR (2002) Cellular electrophysiologic properties of old canine atria provide a substrate for arrhythmogenesis. Cardiovasc Res 54(2):462–469
2.
Biel M, Ruth P, Bosse E, Hullin R, Stuhmer W, Flockerzi V, Hofmann F (1990) Primary structure and functional expression of a high voltage activated calcium channel from rabbit lung. FEBS Lett 269(2):409–412
3.
Blaich A, Welling A, Fischer S, Wegener JW, Kostner K, Hofmann F, Moosmang S (2010) Facilitation of murine cardiac L-type Ca(v)1.2 channel is modulated by calmodulin kinase II-dependent phosphorylation of S1512 and S1570. Proc Natl Acad Sci U S A 107(22):10285–10289. doi:10.1073/pnas.0914287107
4.
Bootman MD, Smyrnias I, Thul R, Coombes S, Roderick HL (2011) Atrial cardiomyocyte calcium signalling. Biochim Biophys Acta 1813(5):922–934. doi:10.1016/j.bbamcr.2011.01.030
5.
Catterall WA (2000) Structure and regulation of voltage-gated Ca2+ channels. Annu Rev Cell Dev Biol 16:521–555. doi:10.1146/annurev.cellbio.16.1.521
6.
Catterall WA, Few AP (2008) Calcium channel regulation and presynaptic plasticity. Neuron 59(6):882–901. doi:10.1016/j.neuron.2008.09.005
7.
Cheng X, Liu J, Asuncion-Chin M, Blaskova E, Bannister JP, Dopico AM, Jaggar JH (2007) A novel Ca(V)1.2 N terminus expressed in smooth muscle cells of resistance size arteries modifies channel regulation by auxiliary subunits. J Biol Chem 282(40):29211–29221. doi:10.1074/jbc.M610623200
8.
Dai S, Hall DD, Hell JW (2009) Supramolecular assemblies and localized regulation of voltage-gated ion channels. Physiol Rev 89(2):411–452. doi:10.1152/physrev.00029.2007
9.
Davies MP, An RH, Doevendans P, Kubalak S, Chien KR, Kass RS (1996) Developmental changes in ionic channel activity in the embryonic murine heart. Circ Res 78(1):15–25
10.
DeMaria CD, Soong TW, Alseikhan BA, Alvania RS, Yue DT (2001) Calmodulin bifurcates the local Ca2+ signal that modulates P/Q-type Ca2+ channels. Nature 411(6836):484–489. doi:10.1038/35078091
11.
Domes K, Ding J, Lemke T, Blaich A, Wegener JW, Brandmayr J, Moosmang S, Hofmann F (2011) Truncation of murine CaV1.2 at Asp-1904 results in heart failure after birth. J Biol Chem 286(39):33863–33871. doi:10.1074/jbc.M111.252312
12.
Feng J, Yue L, Wang Z, Nattel S (1998) Ionic mechanisms of regional action potential heterogeneity in the canine right atrium. Circ Res 83(5):541–551
13.
Fu Y, Westenbroek RE, Yu FH, Clark JP 3rd, Marshall MR, Scheuer T, Catterall WA (2011) Deletion of the distal C terminus of CaV1.2 channels leads to loss of beta-adrenergic regulation and heart failure. J Biol Chem 286(14):12617–12626. doi:10.1074/jbc.M110.175307
14.
Fuller MD, Emrick MA, Sadilek M, Scheuer T, Catterall WA (2010) Molecular mechanism of calcium channel regulation in the fight-or-flight response. Sci Signal 3(141):ra70. doi:10.1126/scisignal.2001152
15.
Gaborit N, Le Bouter S, Szuts V, Varro A, Escande D, Nattel S, Demolombe S (2007) Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart. J Physiol 582(Pt 2):675–693. doi:10.1113/jphysiol.2006.126714
16.
Ganesan AN, Maack C, Johns DC, Sidor A, O’Rourke B (2006) Beta-adrenergic stimulation of L-type Ca2+ channels in cardiac myocytes requires the distal carboxyl terminus of alpha1C but not serine 1928. Circ Res 98(2):e11–e18. doi:10.1161/01.RES.0000202692.23001.e2
17.
Gao T, Cuadra AE, Ma H, Bunemann M, Gerhardstein BL, Cheng T, Eick RT, Hosey MM (2001) C-terminal fragments of the alpha 1C (CaV1.2) subunit associate with and regulate L-type calcium channels containing C-terminal-truncated alpha 1C subunits. J Biol Chem 276(24):21089–21097. doi:10.1074/jbc.M008000200
18.
Grantham CJ, Cannell MB (1996) Ca2+ influx during the cardiac action potential in guinea pig ventricular myocytes. Circ Res 79(2):194–200
19.
Hamilton SL, Yatani A, Brush K, Schwartz A, Brown AM (1987) A comparison between the binding and electrophysiological effects of dihydropyridines on cardiac membranes. Mol Pharmacol 31(3):221–231
20.
Harrell MD, Harbi S, Hoffman JF, Zavadil J, Coetzee WA (2007) Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. Physiol Genom 28(3):273–283. doi:10.1152/physiolgenomics.00163.2006
21.
Hell JW, Yokoyama CT, Wong ST, Warner C, Snutch TP, Catterall WA (1993) Differential phosphorylation of two size forms of the neuronal class C L-type calcium channel alpha 1 subunit. J Biol Chem 268(26):19451–19457
22.
Hudmon A, Schulman H, Kim J, Maltez JM, Tsien RW, Pitt GS (2005) CaMKII tethers to L-type Ca2+ channels, establishing a local and dedicated integrator of Ca2+ signals for facilitation. J Cell Biol 171(3):537–547. doi:10.1083/jcb.200505155
23.
Hulme JT, Lin TW, Westenbroek RE, Scheuer T, Catterall WA (2003) Beta-adrenergic regulation requires direct anchoring of PKA to cardiac CaV1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15. Proc Natl Acad Sci U S A 100(22):13093–13098. doi:10.1073/pnas.2135335100
24.
Hulme JT, Westenbroek RE, Scheuer T, Catterall WA (2006) Phosphorylation of serine 1928 in the distal C-terminal domain of cardiac CaV1.2 channels during beta1-adrenergic regulation. Proc Natl Acad Sci U S A 103(44):16574–16579. doi:10.1073/pnas.0607294103
25.
Jones BW, Brunet S, Gilbert ML, Nichols CB, Su T, Westenbroek RE, Scott JD, Catterall WA, McKnight GS (2012) Cardiomyocytes from AKAP7 knockout mice respond normally to adrenergic stimulation. Proc Natl Acad Sci U S A 109(42):17099–17104. doi:10.1073/pnas.1215219109
26.
Kameyama M, Hofmann F, Trautwein W (1985) On the mechanism of beta-adrenergic regulation of the Ca channel in the guinea-pig heart. Pflugers Arch 405(3):285–293
27.
Kamp TJ, Hell JW (2000) Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C. Circ Res 87(12):1095–1102
28.
Klugbauer N, Welling A, Specht V, Seisenberger C, Hofmann F (2002) L-type Ca2+ channels of the embryonic mouse heart. Eur J Pharmacol 447(2–3):279–284
29.
Koschak A, Reimer D, Huber I, Grabner M, Glossmann H, Engel J, Striessnig J (2001) alpha 1D (Cav1.3) subunits can form l-type Ca2+ channels activating at negative voltages. J Biol Chem 276(25):22100–22106. doi:10.1074/jbc.M101469200
30.
Lemke T, Welling A, Christel CJ, Blaich A, Bernhard D, Lenhardt P, Hofmann F, Moosmang S (2008) Unchanged beta-adrenergic stimulation of cardiac L-type calcium channels in Cav 1.2 phosphorylation site S1928A mutant mice. J Biol Chem 283(50):34738–34744. doi:10.1074/jbc.M804981200
31.
Liu L, O’Hara DS, Cala SE, Poornima I, Hines RN, Marsh JD (2000) Developmental regulation of the L-type calcium channel alpha1C subunit expression in heart. Mol Cell Biochem 205(1–2):101–109
32.
Oliveria SF, Dell’Acqua ML, Sather WA (2007) AKAP79/150 anchoring of calcineurin controls neuronal L-type Ca2+ channel activity and nuclear signaling. Neuron 55(2):261–275. doi:10.1016/j.neuron.2007.06.032
33.
Ouadid H, Seguin J, Richard S, Chaptal PA, Nargeot J (1991) Properties and modulation of Ca channels in adult human atrial cells. J Mol Cell Cardiol 23(1):41–54
34.
Platzer J, Engel J, Schrott-Fischer A, Stephan K, Bova S, Chen H, Zheng H, Striessnig J (2000) Congenital deafness and sinoatrial node dysfunction in mice lacking class D L-type Ca2+ channels. Cell 102(1):89–97
35.
Qu Y, Baroudi G, Yue Y, El-Sherif N, Boutjdir M (2005) Localization and modulation of {alpha}1D (Cav1.3) L-type Ca channel by protein kinase A. Am J Physiol Heart Circ Physiol 288(5):H2123–H2130. doi:10.1152/ajpheart.01023.2004
36.
Qu Y, Boutjdir M (2001) Gene expression of SERCA2a and L- and T-type Ca channels during human heart development. Pediatr Res 50(5):569–574. doi:10.1203/00006450-200111000-00006
37.
Qu Y, Karnabi E, Ramadan O, Yue Y, Chahine M, Boutjdir M (2011) Perinatal and postnatal expression of Cav1.3 alpha1D Ca(2)(+) channel in the rat heart. Pediatr Res 69(6):479–484. doi:10.1203/PDR.0b013e318217a0df
38.
Schram G, Pourrier M, Melnyk P, Nattel S (2002) Differential distribution of cardiac ion channel expression as a basis for regional specialization in electrical function. Circ Res 90(9):939–950
39.
Seisenberger C, Specht V, Welling A, Platzer J, Pfeifer A, Kuhbandner S, Striessnig J, Klugbauer N, Feil R, Hofmann F (2000) Functional embryonic cardiomyocytes after disruption of the L-type alpha1C (Cav1.2) calcium channel gene in the mouse. J Biol Chem 275(50):39193–39199. doi:10.1074/jbc.M006467200
40.
Sun H, Leblanc N, Nattel S (1997) Mechanisms of inactivation of L-type calcium channels in human atrial myocytes. Am J Physiol 272(4 Pt 2):H1625–H1635
41.
Takimoto K, Li D, Nerbonne JM, Levitan ES (1997) Distribution, splicing and glucocorticoid-induced expression of cardiac alpha 1C and alpha 1D voltage-gated Ca2+ channel mRNAs. J Mol Cell Cardiol 29(11):3035–3042. doi:10.1006/jmcc.1997.0532
42.
Van Wagoner DR (2003) Electrophysiological remodeling in human atrial fibrillation. Pacing Clin Electrophysiol 26(7 Pt 2):1572–1575
43.
Wei X, Neely A, Lacerda AE, Olcese R, Stefani E, Perez-Reyes E, Birnbaumer L (1994) Modification of Ca2+ channel activity by deletions at the carboxyl terminus of the cardiac alpha 1 subunit. J Biol Chem 269(3):1635–1640
44.
Welling A, Ludwig A, Zimmer S, Klugbauer N, Flockerzi V, Hofmann F (1997) Alternatively spliced IS6 segments of the alpha 1C gene determine the tissue-specific dihydropyridine sensitivity of cardiac and vascular smooth muscle L-type Ca2+ channels. Circ Res 81(4):526–532
45.
Xu M, Welling A, Paparisto S, Hofmann F, Klugbauer N (2003) Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice. J Biol Chem 278(42):40837–40841. doi:10.1074/jbc.M307598200
46.
Xu XP, Best PM (1990) Increase in T-type calcium current in atrial myocytes from adult rats with growth hormone-secreting tumors. Proc Natl Acad Sci U S A 87(12):4655–4659
47.
Zhang Z, He Y, Tuteja D, Xu D, Timofeyev V, Zhang Q, Glatter KA, Xu Y, Shin HS, Low R, Chiamvimonvat N (2005) Functional roles of Cav1.3(alpha1D) calcium channels in atria: insights gained from gene-targeted null mutant mice. Circulation 112(13):1936–1944. doi:10.1161/CIRCULATIONAHA.105.540070
48.
Zhang Z, Xu Y, Song H, Rodriguez J, Tuteja D, Namkung Y, Shin HS, Chiamvimonvat N (2002) Functional Roles of Ca(v)1.3 (alpha(1D)) calcium channel in sinoatrial nodes: insight gained using gene-targeted null mutant mice. Circ Res 90(9):981–987
49.
Zuhlke RD, Pitt GS, Deisseroth K, Tsien RW, Reuter H (1999) Calmodulin supports both inactivation and facilitation of L-type calcium channels. Nature 399(6732):159–162