AbMole| Benralizumab(CAS号: 1044511-01-4 )

Benralizumab (MEDI-563) 是一种白介素 5 受体 α (IL-5Rα) 定向的溶细胞单克隆抗体，通过增强抗体依赖性细胞介导的细胞毒性诱导嗜酸性粒细胞直接，快速和几乎完全耗尽。

1.化学性质

CAS号	1044511-01-4
储存条件	粉末型式       -20°C   3年；4°C   2年 溶于溶剂       -80°C   6个月；-20°C   1个月
运输方式	冰袋运输，根据产品的不同，可能会有相应调整。

2.参考文献

[1] Joanne E Kavanagh, et al. Chest. Real-World Effectiveness of Benralizumab in Severe Eosinophilic Asthma

[2] Ioana Agache, et al. Allergy. Efficacy and safety of treatment with biologicals (benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab) for severe eosinophilic asthma. A systematic review for the EAACI Guidelines - recommendations on the use of biologicals in severe asthma

[3] No authors listed. N Engl J Med. Benralizumab

[4] Gerard J Criner, et al. N Engl J Med. Benralizumab for the Prevention of COPD Exacerbations

[5] Parameswaran Nair, et al. N Engl J Med. Oral Glucocorticoid-Sparing Effect of Benralizumab in Severe Asthma