Amiloride HCl 是一种吡嗪化合物,通过抑制肾小管上皮细胞的钠离子通道,而抑制钠的重吸收。
1化学性质
分子量 266.09
分子式 C6H8ClN7O.HCl
CAS号 2016-88-8
溶解性(25°C) DMSO 50 mg/mL
储存条件 粉末型式 -20°C 3年;4°C 2年
溶于溶剂 -80°C 6个月;-20°C 1个月
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
2储备液配置
3参考文献
[1] Qianhui Sun, et al. Amiloride: A review
[2] Venkata Yellepeddi, et al. Stability of extemporaneously compounded amiloride nasal spray
[3] Fadel Wedian, et al. Simultaneous spectrofluorometric analysis of tablets containing hydrochlorothiazide combined with timolol maleate or amiloride hydrochloride
[4] Arnault Massink, et al. Allosteric modulation of G protein-coupled receptors by amiloride and its derivatives. Perspectives for drug discovery?
[5] Seema Thakral, et al. Adduction of amiloride hydrochloride in urea through a modified technique for the dissolution enhancement