MCE 国际站:CL264
CAS:1510712-69-2
品牌:MedChemExpress (MCE)
存储条件:Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
生物活性:CL264 是一种用于先天免疫信号研究的TLR7特异性激动剂[1]。
体外:Toll 样受体 (TLR) 是研究最深入的一类受体,在检测一系列基于脂质、蛋白质、核酸的 PAMP 中发挥着重要作用。 TLR7 主要在浆细胞样树突状细胞 (pDC)、巨噬细胞和 B 细胞中表达。许多TLR7调节剂是干扰素诱导剂、抗癌剂、抗感染剂、免疫性疾病治疗剂和疫苗佐剂[1]。
热销产品:Neostigmine (Bromide) | IR-797 (chloride) | PRDX1, Mouse (His) | (S,R,S)-AHPC-PEG3-NH2 (hydrochloride) | BD-2, Mouse | Rovelizumab | Bremelanotide (Acetate) | Phleomycin | Latozinemab | BI-7273
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
参考文献:
[1]. Butterfield JSS, et al. TLR9-Activating CpG-B ODN but Not TLR7 Agonists Triggers Antibody Formation to Factor IX in Muscle Gene Transfer. Hum Gene Ther Methods. 2019 Jun;30(3):81-92.