circos学习笔记（一）：Mac版本安装circos及验证是否可用

1，下载circos，http://circos.ca/software/download/circos/，放置到常用文件夹；

2，选择文件中的circos命令，并添加到Mac的bin文件夹中，使得circos命令可用，类似于pip、conda等命令，如下图：

添加方法：

                   已知circos文件如下：

                               

                   终端执行命令：

                               export PATH=$PATH:`pwd`/circos-0.69-9/bin

3，终端使用，列出circos依赖的Perl包命令：circos -module

上图仅显示部分module结果；

4，若显示missing，则需安装；

先进去：perl -MCPAN -e shell

安装module：install XXX

5，最简单出图
      把下面的内容存储到任意目录下的任意文件比如ehbio.conf下，然后运行circos -conf ehbio.conf就可以获得circos的图circos.png和circos.svg。（建议在终端常用工作目录中使用circos命令）

ehbio.conf内容（引用如下）：

karyotype = data/karyotype/karyotype.human.txt

<ideogram>

<spacing>
default = 0.005r
</spacing>

radius    = 0.9r
thickness = 20p
fill      = yes

</ideogram>

################################################################
# The remaining content is standard and required. It is imported 
# from default files in the Circos distribution.
#
# These should be present in every Circos configuration file and
# overridden as required. To see the content of these files, 
# look in etc/ in the Circos distribution.

<image>
# Included from Circos distribution.
<<include etc/image.conf>>
</image>

# RGB/HSV color definitions, color lists, location of fonts, fill patterns.
# Included from Circos distribution.
<<include etc/colors_fonts_patterns.conf>>

# Debugging, I/O an dother system parameters
# Included from Circos distribution.
<<include etc/housekeeping.conf>>

6，结果显示如下即可：