AbMole| Dupilumab 度普利尤单抗(CAS号：1190264-60-8)

Dupilumab（度普利尤单抗） 是一种潜在首创的（first-in-class），针对 IL-4 受体α (IL-4Rα) 的完全人源化的单克隆抗体，可抑制 IL-4 和 IL-13 信号转导，能用于特应性皮炎和哮喘的相关研究。

化学性质

CAS号	1190264-60-8
储存条件	Please store the product under the recommended conditions in the Certificate of Analysis.
运输方式	冰袋运输，根据产品的不同，可能会有相应调整。

参考文献

[1] Evan S Dellon, et al. N Engl J Med. Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis

[2] Shanthi Narla, et al. J Am Acad Dermatol. Management of inadequate response and adverse effects to dupilumab in atopic dermatitis

[3] F J Muñoz-Bellido, et al. J Investig Allergol Clin Immunol. Dupilumab: A Review of Present Indications and Off-Label Uses

[4] Mario Castro, et al. N Engl J Med. Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma

[5] Marlene Seegräber, et al. Expert Rev Clin Pharmacol. Dupilumab for treatment of atopic dermatitis