(Z)-藁本内酯提取自川芎草，具有抗菌和抗真菌活性 | MedChemExpress (MCE)

(Z)-Ligustilide

中文名：藁本内酯

CAS：81944-09-4

品牌：MedChemExpress (MCE)

存储条件：-20°C, protect from light, stored under nitrogen

生物活性：(Z)-藁本内酯提取自川芎草，具有抗菌和抗真菌活性，平均抗真菌评分为5.6[1]。 (Z)-藁本内酯可抑制 FATP5 和 DGAT 的表达，抑制小鼠的脂肪酸摄取和酯化，具有治疗非酒精性脂肪性肝病 (NAFLD) 的潜力[2]。

详情：www.medchemexpress.cn/z-ligustilide.html

参考文献：

[1]. Rodrigues AMS, et al. The antifungal potential of (Z)-ligustilide and the protective effect of eugenol demonstrated by a chemometric approach. Sci Rep. 2019 Jun 19;9(1):8729. doi: 10.1038/s41598-019-45222-y
[2]. Ma H, et al. Z-ligustilide restores tamoxifen sensitivity of ERa negative breast cancer cells by reversing MTA1/IFI16/HDACs complex mediated epigenetic repression of ERa. Oncotarget. 2017 Apr 25;8(17):29328-29345.
[3]. Lee W, et al. Z-ligustilide and n-Butylidenephthalide Isolated from the Aerial Parts of Angelica tenuissima Inhibit Lipid Accumulation In Vitro and In Vivo. Planta Med. 2019 Jul;85(9-10):719-728.