pandas isin no is in

import pandas as pd

m=pd.DataFrame([[1,2,3],[4,5,6],[7,8,9],[10,11,12]],columns=['a','b','c'])

print('m is \n',m)

m is 
     a   b   c
0   1   2   3
1   4   5   6
2   7   8   9
3  10  11  12

m_in=m[m.c.isin([3,9])]   

print('m_in is \n',m_in)

m_in is 
    a  b  c
0  1  2  3
2  7  8  9

m_notin=m[~m.c.isin([3,4])]  

print('m not in is\n',m_notin) 

m not in is
     a   b   c
1   4   5   6
2   7   8   9
3  10  11  12