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最近在安装PyVCF的时候出问题了，报错如下:
Collecting PyVCF
Downloading PyVCF-0.6.8.tar.gz (34 kB)
Preparing metadata (setup.py) … error
error: subprocess-exited-with-error

× python setup.py egg_info did not run successfully.
│ exit code: 1
╰─> [1 lines of output]
error in PyVCF setup command: use_2to3 is invalid.
[end of output]

note: This error originates from a subprocess, and is likely not a problem with pip.
error: metadata-generation-failed

× Encountered error while generating package metadata.
╰─> See above for output.

note: This is an issue with the package mentioned above, not pip.
hint: See above for details.

解决方法：

pip install PyVCF3

其实就是版本问题，已经更新到PyVCF3了，py3用这个就行。