A clock typically feeds a number of flip-flops. The set of flip-flops being fed by one clock is called itsclock domain. In a typical design, there may be more than one clock domain.
A question of interest is whether the clock domains are related or independent of each other. The answer depends on whether there are any data paths that start from one clock domain and end in the other clock domain.If there are no such paths, we can safely say that the two clock domains are independent of each other. This means that there is no timing path that starts from one clock domain and ends in the other clock domain.