–double-id causes both family and within-family IDs to be set to the sample ID
过滤genotype高missing rate
plink --noweb --bfile chr22 --keep-allele-order --geno 0.5 --set-me-missing --make-bed --out chr22.nomendel
–geno filters out all variants with missing call rates exceeding the provided value (default 0.1) to be removed, while --mind does the same for samples.
–keep-allele-order