R安装GenomicRanges出错问题

R安装GenomicRanges出错问题

凡哥学习R初出茅庐，安装GenomicRanges出错如下

R版本信息：
R version 4.0.3 (2020-10-10) -- "Bunny-Wunnies Freak Out"
Copyright (C) 2020 The R Foundation for Statistical Computing
Platform: x86_64-w64-mingw32/x64 (64-bit)
报错信息：
错误: Bioconductor version cannot be validated; no internet connection?

解决方案

根据R软件的快捷方式找到安装位置，更改 \R-4.0.3\etc\Rprofile.site:
加入：
options(download.file.method=“libcurl”)
options(url.method=‘libcurl’)
如下：

# Things you might want to change

# options(papersize="a4")
# options(editor="notepad")
# options(pager="internal")

# set the default help type
# options(help_type="text")
options(help_type="html")
options(download.file.method="libcurl")
options(url.method='libcurl')

# set a site library
# .Library.site <- file.path(chartr("\\", "/", R.home()), "site-library")

# set a CRAN mirror
# local({r <- getOption("repos")
#       r["CRAN"] <- "http://my.local.cran"
#       options(repos=r)})

# Give a fortune cookie, but only to interactive sessions
# (This would need the fortunes package to be installed.)
#  if (interactive()) 
#    fortunes::fortune()

保存文件，重启R，选好镜像，解决一切安装问题。

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("GenomicRanges")

镜像可在Rstudio上的tools 的Global option选package改选。