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小肽相关1~peptidomic discovery of short open reading frame–encoded peptides in human cells
小肽相关文章分析peptidomic discovery of short open reading frame–encoded peptides in human cellsSEP来自非编码RNA的sORF,并且他们的起始密码子,并不是非经典的AUG,Swiss-Prot数据库里的数据解释大部分小于100aa的小肽,多与细胞外基质的成分相关(2006The Abundance of Shor...原创 2020-01-15 22:21:18 · 392 阅读 · 0 评论 -
PLOS_ONE_Genome-Wide Analysis of Long Noncoding RNA (lncRNA) Expression in Hepatoblastoma Tissues
PLOS_ONE文章复现Genome-Wide Analysis of Long Noncoding RNA (lncRNA) Expression in Hepatoblastoma Tissues目的 对肝癌母细胞瘤进行全基因组分析采用4*180K的LncRNA的芯片以及Sureprint G3 Human lncRNA Chips.并且采用qRT-PCR进行验证。差异的LncRNA...原创 2020-01-15 10:15:04 · 245 阅读 · 0 评论 -
文献阅读High-throughput sequencing of the transcriptome and chromatin accessibility in the same cell
文献阅读汇报 High-throughput sequencing of the transcriptome and chromatin accessibility in the same cell原创 2019-11-08 21:36:06 · 1119 阅读 · 0 评论 -
ATAC-seq以及相关技术(DNase-seq,MNase-seq,NOMe-seq)的发展
ATAC-seq技术及相关技术的发展Reveling in the Revealed这篇文章中,对DNase-seq和ATAC-seq还有MNase-seq相关技术原理以及优缺点进行了总结。具体如下:首先,向我们了解到的,CHIP-seq即染色质免疫共沉淀质谱技术,它主要通过对已知的蛋白,通常是目的转录因子TF免疫沉淀,抓取与该TF结合的DNA片段,然后再进一步的扩增,找到TF的潜在靶基因。...原创 2019-10-27 16:48:54 · 17964 阅读 · 0 评论