遗传图谱和物理图谱的解释

一、遗传图谱(Genetic Map)的概念:

Definition:A genetic map (also called a linkage map) shows the relative location of genetic markers (reflecting sites of genomic variants) on a chromosome. A genetic map is based on the concept of genetic linkage: the closer two markers are to each other on a chromosome, the greater the probability that they will be inherited together. By studying inheritance patterns, the relative order and location of genetic markers along a chromosome can be established.

这段话为遗传图谱的定义,主要涵盖两个要点:

1、遗传图谱展示的是标记在染色体上的相对距离;

2、遗传距离相近的两个标记存在“一起遗传”的现象,即共分离。

Narration:Genetic Map. So, genetic map tells us the location of each gene on the chromosome. It is like having the address of each house along a street. It helps us to appreciate how genetic markers along the chromosome may be inherited together. Closer markers are more likely to be inherited together. And sometimes we refer to this as "blocks."

这段话为遗传图谱的形象化描述,这里引申出了“block”这一个概念,多个连锁的标记(共分离)在一起成为一个block。

(来源:Genetic Map (genome.gov)

二、物理图谱()

Definition

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